Science is the heart of everything we do
As the first ones in the world, we are persistently working on research and development, documenting the potential of the valuable bioactive components from this unique resource.
The different product streams derived from Calanus finmarchicus now have a solid track record of documentation – providing insight to the different areas of impact. For humans and animals alike.
The different product streams derived from Calanus finmarchicus now have a solid track record of documentation – providing insight to the different areas of impact. For humans and animals alike.
Zooca® Calanus Oil is a novel bioactive fat that is more than just an omega-3. Containing a full spectrum fatty acid profile. Oil from Calanus finmarchicus naturally has 40 different fatty acid, bound in their natural form.
Health benefits
Feeling stronger for longer
Most of the benefits we see are related to muscles in some way; we see it on the pumping efficiency of the heart. Muscle function of the big muscle group and also the grip strength in hands and on overall muscle benefits. We have seen an increased muscle mass formation, decrease in body fat, improvements in insulin sensitivity and once again showing that the oil we have also have a high bioavailability underlined by the omega-3 index findings.
What is calanus oil made of:
What makes it unique?
This uniqueness of Zooca® Calanus Oil lies in its chemical structure, primarily composed of wax esters that contain bioactive compounds. This special composition distinguishes it from any other marine and plant oils.
Strong scientific foundation - Zooca® Calanus Oil
Clinical and preclinical studies so far have been focusing on screening for effects and mechanisms in humans to document safety and uptake. Since the beginning of the scientific exploration, the volume of scientific publications and theses are continuously growing. So far, ten doctoral candidates have been involved inZooca® Calanus Oil research, and numerous peer-reviewed papers have been produced in the areas of biomedical and biochemical science. The findings so far have attracted much attention.
Safety and bioavailability have been documented in several human studies. The bioavailability study showed that Zooca® Calanus Oil gives a twofold uptake compared to ethyl esters, confirming that the Zooca® Calanus Oil are digested, and its fatty acids absorbed and a recently conducted study confirmed these data by revealing a remarkable 21% increase in the omega-3 index (sum of EPA and DHA in red blood cells) from a 12 week intervention
Several doctoral students and researchers are engaged in ongoing projects related to mechanistic and preclinical studies, as well as clinical trials directly related to the impact of Zooca® Calanus Oil. The company is currently involved in several human clinical trials within the areas of metabolic health and a big intervention study on children with ADHD.
Future studies will become increasingly more targeted towards specific effects, and the long-term goal is to qualify for one or more approved health claims in the EU and other
Future studies will become increasingly more targeted towards specific effects, and the long-term goal is to qualify for one or more approved health claims in the EU and other
More than fatty acids: marine policosanols
The wax esters in Zooca® Calanus Oil contain bioactive lipid molecules which resemble long-chain monounsaturated fatty acids. These are often referred to as policosanols due to its alcohol moiety (-ols). Nearly 40 % of the Zooca® Calanus Oil are present as the policosanols eicosenol and docosenol, which constitute the major part of the alcohol fraction. These special biomolecules are entirely made from de novo biosynthesis by the zooplankton. Initially, the fatty acids are built and subsequently reduced to the corresponding policosanol.
Long-chain alcohols from terrestrial sources such as rice bran wax and sugar cane wax have been shown to increase physical performance and exert anti-inflammatory effects. It has been suggested that the long-chain fatty alcohols enhance physical performance through sparing of muscle glycogen stores by increasing the lipid oxidatio. However, there are few studies on the effects of marine fatty alcohols and further investigation is thus required.
Long-chain alcohols from terrestrial sources such as rice bran wax and sugar cane wax have been shown to increase physical performance and exert anti-inflammatory effects. It has been suggested that the long-chain fatty alcohols enhance physical performance through sparing of muscle glycogen stores by increasing the lipid oxidatio. However, there are few studies on the effects of marine fatty alcohols and further investigation is thus required.
High content of EPA precursor stearidonic acid, boosting EPA levels
Decades of research support that higher intake of EPA and DHA is associated with reduced risk of mortality from coronary heart disease and sudden cardiac death. In addition to EPA and DHA, Zooca® Calanus Oil is especially rich in stearidonic acid (SDA). This is the first metabolite formed directly from alpha-linolenic acid, which is poorly converted to EPA and DHA in the body. SDA is by far more efficiently converted further to EPA than ALA and has been referred to as being a ‘pro-EPA’ fatty acid. This has led to the suggestion of a direct intake of SDA as another strategy to increase tissue EPA levels. Consequently, SDA has recently gained more attention. Several studies show beneficial effects exerted by the fatty acids as an independent entity, and not only as an effective precursor to EPA. Stearidonic acid favourably compares with dietary EPA in side-by-side experiments in a limited number of studies.
